[Q] Sim card not detected, IMEI ok, CARD READER is new

Hello, I have a problem with my 2x , it no longer recognizes the sim card , I have change the sim card reader , I checked and even try to rewrite IMEI but nothing changed , this happened after flash stock 2.2 (all same the stock V10a) or after flash CWM and CM7.2 i don't really know.
Anyway I'm stuck and I do not know what to do to solve the problem
Please help me.